The comparison of collapsibility of internal jugular veins, subclavian veins and inferior vena cava as a predictor of fluid responsiveness in patients on pressure support ventilation: a prospective cohort study.

The comparison of collapsibility of internal jugular veins, subclavian veins and inferior vena cava as a predictor of fluid responsiveness in patients on pressure support ventilation: a prospective cohort study. - The comparison of collapsibility of internal jugular veins, subclavian veins and inferior vena cava as a predictor of fluid responsiveness in patients on pressure support ventilation.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000021449

Enrollment

Registered

2016-03-14

Start date

2014-03-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients on pressure support ventilation were prospectively included when fluid challenges were clinically indicated.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The study patients were (1) intubated, mechanically ventilated on pressure support ventilation, (2) in acute circulatory failure. Acute circulatory failure was defined as (1) a systolic blood pressure lesser than 90mmHg (or mean arterial pressure lesser than 65mmHg) or the need for vasopressive drugs, (2) a urine output below 0.5ml/kg/hr for at least 2 hours, (3) tachycardia (heart rate >100bpm), (4) the presence of skin mottling

Exclusion criteria

Exclusion criteria: Patients with elevated intracranial hypertension, abdominal compartment syndrome, pulmonary embolism, pulmonary hypertension, severe acute respiratory distress syndrome (ARDS), positive end expiratory pressure (PEEP) higher than 10cmH2O, severe left ventricular dysfunction (ejection fraction lesser than 30%), irregular heart rhythm, occlusion of IJVs or SCVs or IVC was excluded

Design outcomes

Primary

Measure	Time frame
To evaluate utility of collapsibility of internal jugular veins (IJVs) and subclavian veins (SCVs) in comparison with collapsibility of IVC to predict fluid responsiveness on pressure support ventilation. Fluid responsiveness was defined as 8% increase of stroke volume calculated with arterial pulse contour analysis after passive leg raising (PLR).	—

Countries

Japan

Contacts

Public ContactYusuke Iizuka

Shonan Kamakura General Hospital Critical Care

yiizuka@jichi.ac.jp0467461717

Outcome results