The Effectiveness of high performance CPR for out-of-hospital cardiac arrests: a randomized control trial

Real-time Feedback, Debriefing, and Retraining for System-Level High-Quality CPR - REFRESH-OHCA Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021431

Enrollment

3020

Registered

2016-03-11

Start date

2016-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Out-of-hospital cardiac arrests

Interventions

To perform cardiopulmonary resuscitation with real-time feedback and debriefing by using CPR feedback device To perform cardiopulmonary resuscitation without real-time feedback and debriefing by using

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients 18 years old or older with medical cause related out-of-hospital cardiac arrest who received cardiopulmonary resuscitation by emergency medical services personnel

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Do-not attempt-resuscitation order 3. Refused to participate

Design outcomes

Primary

Measure	Time frame
Favorable neurological survival at 1 month or at hospital discharge, whichever occurred first, assessed using the Cerebral Performance Category (CPC) scale	—

Secondary

Measure	Time frame
1. Patient outcomes Survival(1 month or at hospital discharge, whichever occurred first) Prehospital return of spontaneous circulation 2. The data on CPR quality Chest compression fraction Chest compression depth Chest compression rate Ventilation rate	—

Countries

Japan

Contacts

Public ContactNorihiro Nishioka

Kyoto University Department of Preventive Services

nishioka.norihiro.26x@kyoto-u.jp075-753-4400

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026