A multicenter randomized controlled study evaluating 25G needle with a core trap for EUS guided fine needle biopsy in diagnosis of malignancy of pancreatic neuroendocrine tumors

A multicenter randomized controlled study evaluating 25G needle with a core trap for EUS guided fine needle biopsy in diagnosis of malignancy of pancreatic neuroendocrine tumors - Evaluating 25G needle with a core trap for EUS guided fine needle biopsy in diagnosis of malignancy of pancreatic neuroendocrine tumors

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021409

Enrollment

Registered

2016-04-01

Start date

2016-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic neuroendocrine tumor

Interventions

25G EUS-FNA needle with a core trap

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Pancreatic neuroendocrine tumor diagnosed by imaging modalities 2. Requirement of EUS-FNA for deciding surgical resection 3. ECOG performance status = 1, 2 4. No severe dysfunction in other organs 5. Written informed consent obtained from patients

Exclusion criteria

Exclusion criteria: 1. Presence of intervening vessels or other organs on the puncture line 2. High risk of complications (bleeding, tumor seeding) 3. Inability to obtain informed consent

Design outcomes

Primary

Measure	Time frame
Concordance rates of pancreatic neuroendocrine tumor grading by EUS-FNA with grade of the resected tumor, measuring the Ki-67 index in EUS-FNA specimens	—

Countries

Japan

Contacts

Public ContactKen Kamata

Kinki University Faculty of Medicine Department of Gastroenterology and Hepatology

ky11@leto.eonet.ne.jp072-366-0221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026