Effects of food intake and 4-week multiple curcumin ingestion on pharmacokinetics (bioavailability) of a curcumin supplement

Effects of food intake and 4-week multiple curcumin ingestion on pharmacokinetics (bioavailability) of a curcumin supplement - Pharmacokinetics (bioavailability) of of a curcumin supplement

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021406

Enrollment

Registered

2016-11-01

Start date

2016-03-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Curcumin supplement Single oral dose of the supplement containing 30 mg of curcumin, twice a day for 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Subjects signed on informed consent documents - Healthy male and female Japanese subjects at the age between 20 and 45 - Non-smoker - Body weight <= 80 kg - 20<=BMI<25 - Subjects whoeat 3 meals a day regulary

Exclusion criteria

Exclusion criteria: - Severe disease history - Currently under treatment - Food or drug allergy - Regular use of curcumin-containing supplements - Pregnant or planned on becoming pregnant - Other unappropriate conditions judged by PI

Design outcomes

Primary

Measure	Time frame
Pharmacokinetics parameters (AUC, Cmax, baseline plasma curcumin concetration)	—

Secondary

Measure	Time frame
MDA, 8-OHdG, metabolome	—

Countries

Japan

Contacts

Public ContactMakoto Terashima

Oneness Support Co., Ltd. Director

mterashima@oneness-sup.co.jp06-4801-8917

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026