A study of detection of colitic neoplasia in patients with ulcerative colitis following sensitization with oral 5-aminolevulinic acid using autofluorescence endoscopy

A study of detection of colitic neoplasia in patients with ulcerative colitis following sensitization with oral 5-aminolevulinic acid using autofluorescence endoscopy - A study of detection of colitic neoplasia in patients with ulcerative colitis following sensitization with oral 5-aminolevulinic acid using autofluorescence endoscopy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021402

Enrollment

Registered

2016-03-16

Start date

2010-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis

Interventions

Autofluorescence endoscopy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients who have diagnosed ulcerative colitis clinically and histopathologically (Duration of disease 8 years or more; pancolitis or left-sided colitis) 2)Lichtiger index<=5 3)Patients who understand the concept of the study and allow to participate in the study with certificate document.

Exclusion criteria

Exclusion criteria: 1)Patients suspected or diagnosed of coagulation disorder or porphyria 2)Patients who are under 18 years old 3)Patients who investigator judged ineligible to register

Design outcomes

Primary

Measure	Time frame
The efficacy of autofluorescence endoscopy with 5-aminolevulinic acid for colitis associated carcinoma or dysplasia	—

Secondary

Measure	Time frame
The estimation of fluorescence signal patterns in colitis associated carcinoma or dysplasia	—

Countries

Japan

Contacts

Public ContactTetsuyoshi Iwasaki

The Jikei University School of Medicine Gastroenterology and Hepatology

tkato@jikei.ac.jp03-3433-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026