The effect of ventilatory tidal volume on lung injury during hepatectomy that requires transient liver blood flow interruption.

The effect of ventilatory tidal volume on lung injury during hepatectomy that requires transient liver blood flow interruption. - The effect of ventilatory tidal volume on lung injury during hepatectomy that requires transient liver blood flow interruption.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021371

Enrollment

Registered

2016-03-07

Start date

2007-08-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients undergo hepatectomy

Interventions

Patients were ventilated with a tidal volume of 12 mL per predicted body weight (kg). Patients were ventilated with a tidal volume of 6 mL per predicted body weight (kg).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients undergoing hepatectomy

Exclusion criteria

Exclusion criteria: Patients with an American Society of Anesthesiologists' physical status (ASA-PS) value of 3 and above, pre-existing lung disease, tumor in the portal vein or inferior vena cava, requirement of bile duct or gastrointestinal tract repair, or requirement of additional surgical procedures other than hepatectomy

Design outcomes

Primary

Measure	Time frame
proinflammatory cytokine concentration in epithelial lining fluid during surgery	—

Secondary

Measure	Time frame
oxygenation just after the surgery	—

Countries

Japan

Contacts

Public ContactKiyoyasu Kurahashi

Yokohama City University Graduate School of Medicine Department of Anesthesiology and Critical Care Medicine

kiyok@med.yokohama-cu.ac.jp045-787-2918

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026