Implication of intraoperative radiotherapy in rectal cancer surgery with the preservation of voiding and sexual function

Implication of intraoperative radiotherapy in rectal cancer surgery with the preservation of voiding and sexual function - Implication of intraoperative radiotherapy in rectal cancer surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021353

Enrollment

100

Registered

2016-03-04

Start date

2004-02-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

advanced lower rectal cancer

Interventions

Intraoperative radiotherapy (IORT) group:rectal resection(excision),bilateral lateral lymphnode dissection, complete preservation of pelvic autonomic nerves , IORT radiation frequency: once cone siz

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1 Histologically proven adenocarcinoma 2 The lower edge of the tumor below the peritoneal reflection 3 The depth of tumor invasion beyond the proper muscle layer or positive mesorectal node metastasis 4 Liver, lung, renal and cardiac functions well preserved 5 No previous history of advanced colon and other organ malignancies

Exclusion criteria

Exclusion criteria: 1 informed consent not obtainable 2 presence of severe complications

Design outcomes

Primary

Measure	Time frame
5-year local recurrence rate	—

Secondary

Measure	Time frame
5-year overall survival, 5-year disease-free survival, complication rates (small bowel obstruction, pelvic abscess), voiding function	—

Countries

Japan

Contacts

Public ContactTadahiko Masaki

Kyorin University Surgery

masaki@ks.kyorin-u.ac.jp0422-47-5511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026