allergic conjunctivitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: *Healthy individuals who had not used contact lenses for at least 1 day before the study. *Healthy individuals aged 20 years and older at the time of informed consent. *Healthy individuals that received a full explanation on the objectives and methods of the study, expected effects and adverse drug reactions, respect for the privacy, recompense and compensation, and who themselves or their legal representatives voluntarily provided consent for study participation.
Exclusion criteria
Exclusion criteria: Subject who the investigator considers ineligible for enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Observation of corneal epithelium disorders (1) Fluorescein vital staining (2) Fluorophotometry 2. Evaluation of corneal epithelial mucin layer (1) Lissamine green vital staining | — |
Secondary
| Measure | Time frame |
|---|---|
| Fluorescein staining (2microL) was performed and evaluated initially, by an ophthalmologist before eye washing. Eyes were washed with 20 mL of BSS-plus after 10 minutes to wash away the fluorescein stain solution and, 20 minutes later (30 minutes after fluorescein staining), fluorescein remaining on the cornea was measured using the fluorophotometry. Following this, evaluation by lissamine green staining (2microL) was performed. After eye washing, fluorescein staining evaluation, fluorophotometry measurements, and lissamine green staining evaluation were performed in the same manner as before eye washing, and the results were compared before and after eye washing. | — |
Countries
Japan
Contacts
Tsurumi University Faculty of Dentistry