Chronic constipation
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients who have constipation as chief complaint. 2) Without mechanical obstruction such as colon cancer. 3) Patients who are between 20 and 80 years old with ability for agreement. 4) Written informed consent was obtained after sufficient explanation.
Exclusion criteria
Exclusion criteria: 1) Patients with organic digestive tract disease before 1 year. 2) Subjects with contraindications to MRI.(such as detained internal metal, or claustrophobia.) 3) Patients with past history of gastrointestinal excision. (without appendectomy) 4) Patients judged inappropriate for the trial by investigators such as severe heart failure, hepatic failure, renal failure, and terminal cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between the colonic contents and the symptoms: correlation between the homology of colonic contents of ascending colon and sigmoid colon, and GSRS score or Bristol scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Correlation between the colonic contents and the environmental factor: correlation between the homology of colonic contents of ascending colon and sigmoid colon, and the medication or last meal or last defecation. 2) Correlation between the luminal diameter of colon and the symptoms: correlation between the maximal diameter of ascending and sigmoid colon, and GSRS score or Bristol scale. 3) Correlation between the luminal diameter of colon and the environmental factor: correlation between the maximal diameter of ascending and sigmoid colon , and the medication or last meal or last defecation. | — |
Countries
Japan
Contacts
Yokohama City University School of Medicine Department of Gastroenterology and Hepatology