The observational study to search for the predictors of the changes of body weight and composition by intensive lifestyle modification for the patients with metabolic syndrome

The observational study to search for the predictors of the changes of body weight and composition by intensive lifestyle modification for the patients with metabolic syndrome - The predictors of the changes of body weight and composition

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021256

Enrollment

150

Registered

2016-02-29

Start date

2016-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes and obesity patients

Interventions

All patients received intensive medical therapy and lifestyle modification, including calorie restriction and regular exercise. The content of lifestyle guidance was varied individually during hospita

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with type 2 diabetes or obesity who were hospitalized in Tokyo Medical and Dental University Hospital for the purpose of glycemic control or weight reduction.

Exclusion criteria

Exclusion criteria: Patients with severe renal impairment (estimated glomerular filtration rate [eGFR] < 15 mL/min/1.73 m2 or undergoing renal replacement therapy), pregnant women, and those with infectious or malignant diseases were excluded.

Design outcomes

Primary

Measure	Time frame
The changes of body weight, appendicular lean soft tissue mass and body fat percentage during 6 months follow-up.	—

Secondary

Measure	Time frame
The changes of visceral and subctaneous fat area during 6 months follow-up.	—

Countries

Japan

Contacts

Public ContactIsao Minami

Tokyo Medical and Dental University Department of Molecular Endocrinology and Metablism

iminami.mem@tmd.ac.jp03-3813-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026