Breast cancer
Conditions
Interventions
None listed
Sponsors
Tokyo Medical and Dental University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Primary registration 1) Tumor =<3 cm 2) cN0M0 3) Tumor is both unifocal and unicentric 4) Pathologically proven ductal, mucinous, tubular medullary, colloid, or lobular carcinoma 5) No prior history of breast cancer/ no bilateral breast cancer 6) No prior radiotherapy or chemotherapy for this breast cancer 7) Female and >40 years old 8) ECOG performance status 0-1 9) Informed consent was given Secondary registration 1) Primary registration had been done 2) Breast conserving surgery was performed 3) Pathologically tumor <3 cm 4) Pathologically proven ductal, mucinous, tubular medullary, colloid, or lobular carcinoma after surgery 5) No extensive intraductal component 6) No lympho-vascular invasion 7) Surgical margin was not positive 8) pN0 9) Chemotherapy will be performed over 2 weeks later
Exclusion criteria
Exclusion criteria: Primary registration 1) Prior history of radiotherapy for chest 2) During pregnancy or lactating 3) Collagen disease 4) Psychiatric comorbidities 5) Prior invasive malignancy unless disease free for a minimum of 5 years 6) Uncontrolled diabetes mellitus 7) Attending physician believes the patient is not suitable for this study Secondary registration 1) No conserving surgery 2) Paget disease 3) Unsuitable state for brachytherapy 4) Cosmetic evaluation is fair or poor before brachytherapy 5) Duration between surgery and brachytherapy was over 8 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local control rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression free survival rate Overall survival rate Complications Cosmetic evaluation | — |
Countries
Japan
Contacts
Public ContactRyoichi Yoshimura
Tokyo Medical and Dental University Hospital Department of Radiation Therapeutics and Oncology
Outcome results
None listed