The association between coronary plaque characteristics and glucose fluctuation assesed by coronary imaging devices and continuous glucose monitoring

The association between coronary plaque characteristics and glucose fluctuation assesed by coronary imaging devices and continuous glucose monitoring - The Association Between Coronary plaque characteristics and glucose fluctuation assesed by coronary imaging devices and Continuous Glucose Monitoring:ABC-CGM study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000021228

Enrollment

200

Registered

2016-02-27

Start date

2015-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina pectoris with impaired glucose torerance or diabetes mellitus and patients who are suspected that disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Prospective observational study Patients with impaired glucose torelance who have a plan to receive PCI for coronary artery disease. Patinets with diagnosed or suspected impaired glucose torelance who had a history of coronary stenting.

Exclusion criteria

Exclusion criteria: 1)Patients with renal dysfunction(Creatinin level is more than 2.0mg/ml) or reciving hemodaialysis. 2)the patients who have had heart failure (NYHA >III) 3)patients with any malignant tumor or very ill condition 4)pregnant women or women at risk of becoming pregnant

Design outcomes

Primary

Measure	Time frame
1.Coronary plaque characteristics and neointimal characteristics in stent using the optical coherence tomography (OCT) and intravascular ultrasound(IVUS) and coronary angiography at the time of treatment, nine(six to twelve)months and three(twe to four)years. 2.Circadian rhythm in the blood glucose using CGM 3.Association between atherosclerosis assessed by IVUS or OCT and subsets of monocyte and Tcell.	—

Measure

Time frame

1.Coronary plaque characteristics and neointimal characteristics in stent using the optical coherence tomography (OCT) and intravascular ultrasound(IVUS) and coronary angiography at the time of treatment, nine(six to twelve)months and three(twe to four)years. 2.Circadian rhythm in the blood glucose using CGM 3.Association between atherosclerosis assessed by IVUS or OCT and subsets of monocyte and Tcell.

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Secondary

Measure	Time frame
The following at the time of treatment, nine(six to twelve)months and three(twe to four)years 1.Glucose, IRI, CPR assesed by glucose tolerance test. 2.Intima- media thickness(IMT) assesed by carotid artery ultrasound. 3.Endothelial function assessed by FMD. 4.Monocyte and T lymphocyte assesed by flowcytometry. 5.Bacterial flora in the intestine. 6.Inflammatory cell marker associated with arteriosclerosis.	—

Measure

Time frame

The following at the time of treatment, nine(six to twelve)months and three(twe to four)years 1.Glucose, IRI, CPR assesed by glucose tolerance test. 2.Intima- media thickness(IMT) assesed by carotid artery ultrasound. 3.Endothelial function assessed by FMD. 4.Monocyte and T lymphocyte assesed by flowcytometry. 5.Bacterial flora in the intestine. 6.Inflammatory cell marker associated with arteriosclerosis.

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Countries

Japan

Contacts

Public ContactHiroyuki Yamamoto

Kobe university hospital Cardiovascular medicine

y0493589m@hotmail.co.jp078-382-5111

Outcome results