Effects of continous plasma filtration with dialysis therapy in severe septic patients with acute liver failure

Effects of continous plasma filtration with dialysis therapy in severe septic patients with acute liver failure - Effects of CPDF in severe septic patients with acute liver failure

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021225

Enrollment

Registered

2016-02-27

Start date

2016-02-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe sepsis with acute liver failure

Interventions

CPDF therapy (+) It is possible to treat CPDF therapy for 7 days.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with both the criteria of sepsis and the criteria of acute liver failure. Sepsis is defined as SIRS with infection. Acute liver failure is defined as PT 40% or PT-INR >1,5 within 8 weeks.

Exclusion criteria

Exclusion criteria: 1) During pregnancy or breast-feeding 2) The doctor has been deemed inappropriate 3) Not obtain consent from the patient or families

Design outcomes

Primary

Measure	Time frame
Changes in the severity score (APACHE II and SOFA) at 5 days after CPDF therapy	—

Secondary

Measure	Time frame
Duration of ICU stay, duration of hospitality, survival rate at 28day after CPDF therapy, and changes in hemodynamics and respiratory function and biochemical data	—

Countries

Japan

Contacts

Public ContactTakumi Taniguchi

Kanazawa University Hospital Intensive Care Unit

ttaniyan@med.kanazawa-u.ac.jp076-265-2430

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026