Minimum effective dose of lactulose for intestinal function. exploratory study

Minimum effective dose of lactulose for intestinal function. exploratory study - Minimum effective dose of lactulose for intestinal function.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021219

Enrollment

Registered

2016-03-15

Start date

2016-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intake of lactulose 1, 2, 3g/day for 2weeks sequentially

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Subjects with feces frequency 2-4 times / week

Exclusion criteria

Exclusion criteria: 1) Subjects with severe hepatic, renal, heart, gastrointestinal, cerebrovascular, endocrine, metabolic or infection diseases. 2) Subjects with the history of gastrointestinal resection. 3) Subjects with gastrointestinal dysfunction such as irritable bowel syndrome or inflammatory bowel disease. 4) Subjects who use medicines or supplements that may influence feces frequency; e.g. antibiotics, probiotics, laxatives, antidiarrheals, fibers. 5) Subjects with milk allergy. 6) Subjects who participate another study. 7) Subjects who are judged inappropriate for the study by the investigator or the physician.

Design outcomes

Primary

Measure	Time frame
Feces frequency, Feces hardness	—

Secondary

Measure	Time frame
Intestinal bacteria number	—

Countries

Japan

Contacts

Public ContactHisakazu Iino

Showa Women's University Graduate School, Science for Living System

iino@swu.ac.jp03-3411-4828

Outcome results