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Studies in the effects of dietary intake of broccoli sprouts on intestinal microflora and bowel movements in healthy human subjects.

Studies in the effects of dietary intake of broccoli sprouts on intestinal microflora and bowel movements in healthy human subjects. - Effects of BS intake on human intestinal microflora

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000021207
Enrollment
48
Registered
2016-03-01
Start date
2016-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy human subjects with mild constipation

Interventions

Intervention Group (24 cases) Broccoli Sprouts 20g/day for 4 weeks (Sulforaphane Glucosinolate 88 mg/day) Placebo Group (24 cases) Alfalfa Sprouts 20g/day for 4 weeks (Sulforaphane Glucosinola

Sponsors

Univeristy of Tsukuba
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: healthy human subects without organic gastrointestinal diseases, and with mild constipation, whose constipation assessment score (CAS) is greater than 1.

Exclusion criteria

Exclusion criteria: Subjects 1) with organic gastrointestinal diseases 2) with allergy to broccoli or alfala 3) with taking any drugs, which affects intestinal microflora, and bowel movements (e.g. NSAIDs, antibiotics,laxatives)

Design outcomes

Primary

MeasureTime frame
Intestinal microflora at 4 weeks after starting intake of broccoli sprouts(BS), and at 4 weeks after finishing intale of BS.

Secondary

MeasureTime frame
Constipation Assessment Scale Bristol Stool Scale

Countries

Japan

Contacts

Public ContactYanaka, Akinori

Faculty of Medicine, University of Tsukuba Hitachi Medical education and Research Center

ynk-aki@md.tsukuba.ac.jp0294-23-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026