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Study to evaluate the effectiveness and saftyof the mFOLFOX+bevacizumab combination therapy for bladder adenocarcinoma

Study to evaluate the effectiveness and saftyof the mFOLFOX+bevacizumab combination therapy for bladder adenocarcinoma - Study to evaluate the effectiveness and saftyof the mFOLFOX+bevacizumab combination therapy for bladder adenocarcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000021193
Enrollment
5
Registered
2016-02-25
Start date
2014-08-15
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bladder adenocarcinoma

Interventions

Administration of oxaliplatin, fluorouracil, levofolinate and bevacizumab

Sponsors

Nagoya City University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.The patients who have a diagnosis of a bladder adenocarcinoma histologically 2.The patients who are resistant to clinical trial S1+CDDP for the bladder adenocarcinoma and GD therapy of 2nd line for the urothelial carcinoma. 3.The patients who do not use bebacizumab

Exclusion criteria

Exclusion criteria: 1.Case with serious myelosuppression 2.Case with the diarrhea (stools watery) 3.Case who had a serious infection 4.A large quantity of ascitic fluid, case with the pleural effusion 5.Case with serious heart disease or the anamnesis 6.The case that overall status worsens 7.Case with severe dysesthesia with the functional disorder or the dysesthesia 8.A pregnant woman or the case that may be pregnant and nursing mother 9.It is a case with a history of hypersensitivity for an ingredient including, levofolinate, fluorouracil, oxaliplatin and other platinum

Design outcomes

Primary

MeasureTime frame
response rate

Countries

Japan

Contacts

Public ContactNoriyasu Kawai

Nagoya City University Graduate School of Medical Sciences Department of Nephro-urology

n-kawai@med.nagoya-cu.ac.jp052-853-8266

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026