Safety and efficacy of botulinum toxin injection therapy on patients with esophageal motility disorders

Safety and efficacy of botulinum toxin injection therapy on patients with esophageal motility disorders - botulinum toxin injection therapy for esophageal motility disorders

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021190

Enrollment

Registered

2016-02-25

Start date

2016-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal motility disorders except for achalasia

Interventions

Botulinum toxin injection therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with esophageal motility abnormalities except for achalasia

Exclusion criteria

Exclusion criteria: 1. Patients with neuromuscular disorders 2. Patients who have esophageal varices 3. Patients whose esophagus is excluded by other organs 4. Patients with severe respiratory dysfunction 5. Pregnant patients or patients nursing a child 6. Patients who have allergy for botulinum toxin 7. Patients who are considered as an inappropriate subject for the study

Design outcomes

Primary

Measure	Time frame
Improvement of symptoms	—

Secondary

Measure	Time frame
Safety of botulinum toxin injection therapy duration of botulinum toxin injection therapy's effect	—

Countries

Japan

Contacts

Public ContactShiko Kuribayashi

Gunma University Hospital Department of Gastroenterology and Hepatology

shikokuri@yahoo.co.jp027-220-8137

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026