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Study of the influence of instillation period of perioperative antibacterial opthalmic solution on human conjunctival flora

Study of the influence of instillation period of perioperative antibacterial opthalmic solution on human conjunctival flora - Study of the influence of instillation period of perioperative antibacterial opthalmic solution on human conjunctival flora

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000021186
Enrollment
100
Registered
2016-02-25
Start date
2015-04-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient underwent cataract surgery

Interventions

Topical instillation: levofloxacin 1.5% ophthalmic solution 4 times per day Administration period after cataract surgery: One week, 50 patients, 50eyes. Topical instillation: levofloxacin 1.5% opht

Sponsors

Miyata Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients with bacteria examination within three months of cataract surgery. 2) Patients to obtain the written consent

Exclusion criteria

Exclusion criteria: 1) Patients with a history of antibiotics prescription within three months prior to the study. 2) Patients with a history of hypersensitivity or severe adverse effects by fluoroquinolones. 3) Glaucoma patients treated with ophthalmic solutions 4) Patients under steroid ophthalmic solutions 5) Patients under immunosuppressive therapy 6) Patients suspecting to be any infectious ocular diseases. 7) Patients whom investigators considered not to be are eligible.

Design outcomes

Primary

MeasureTime frame
Antibiotic susceptibility of isolated bacteria (pre operation,end of instillation, post 1 3 6 9 12 months)

Secondary

MeasureTime frame
Prevalenced bacterialin species in the conjunctiva flora. Change of antibiotic resistant.

Countries

Japan

Contacts

Public ContactRyohei NEJIMA

Miyata Eye Hospital Miyata Eye Hospital

nejima@miyata-med.ne.jp0986-22-1441

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026