Effects of Long-acting Loop Diuretics in Heart Failure with Reduced Ejection Fraction Patients with Cardiac Resynchronization Therapy

Effects of Long-acting Loop Diuretics in Heart Failure with Reduced Ejection Fraction Patients with Cardiac Resynchronization Therapy - Effects of long-acting loop diuretics in heart failure patients with reduced ejection fraction.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021162

Enrollment

Registered

2016-02-23

Start date

2013-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure

Interventions

We randomly allocated all patients into 2 groups using the envelope method. We used furosemide as short-acting loop diuretics, whereas azosemide as long-acting loop diuretics. In the furosemide gr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients implanted with a cardiac resynchronization therapy device who had previously taken loop diuretics were enrolled in this study.

Exclusion criteria

Exclusion criteria: The exclusion criteria were 1) any changes pertaining to medication use within 1 month, 2) patients planning an admission to a hospital within the next 3 month for any reasons, and 3) patients undergoing haemodialysis.

Design outcomes

Primary

Measure	Time frame
The primary endpoints were the variation of fluid index and thoracic impedance measured by cardiac resynchronization therapy at 6 months.	—

Countries

Japan

Contacts

Public ContactMasahiko Asami

Cardiology Cardiology

asami560725@yahoo.co.jp+81-3-3862-9111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026