Adjustment of inspired oxygen concentration during general anesthesia using Oxygen Reserve Index (ORI) a new parameter of oxygenation reserve potential.

Adjustment of inspired oxygen concentration during general anesthesia using Oxygen Reserve Index (ORI) a new parameter of oxygenation reserve potential. - Adjustment of inspired oxygen concentration during general anesthesia using Oxygen Reserve Index (ORI) a new parameter of oxygenation reserve potential.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021118

Enrollment

Registered

2016-02-21

Start date

2016-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with ASA (American Society of Anesthesiologists) classification 1 or 2 who are scheduled for surgical procedures under general anesthesia

Interventions

To measure ORI, a sensor similar in form to a pulse oximeter sensor is applied to the third or fourth finger of each patient for a duration lasting from admission to the operating room until the end o

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are scheduled for surgical procedures under general anesthesia, and who meet all of the following conditions: 1. ASA (American Society of Anesthesiologists) classification 1 or 2. 2. Submission of written informed consent for this study. 3. After general anesthesia induction at the operating room, a catheter for blood pressure measurement is inserted in the artery when necessary for the surgery.

Exclusion criteria

Exclusion criteria: Patients are excluded if they meet any of the following conditions: 1. Inability to wear the sensor due to deformity or hypoperfusion of fingers. 2. Preoperative anemia due to hemoglobinopathies (e.g. sickle cell disease, thalassemia) 3. Cardiac or pulmonary disease (e.g. chronic obstructive pulmonary disease, interstitial pneumonia) 4. Ineligibility for participation in the study

Design outcomes

Primary

Measure	Time frame
PaO2 obtained by arterial blood gas analysis, and the ORI and inspired oxygen concentration at the time of blood colection during general anesthesia	—

Secondary

Measure	Time frame
1. Basic information of patients: Gender, age, height, weight, date of surgery, diagnosis, operative procedure, sensor attachment site, and insertion site of the arterial pressure line. 2. Presence or absence of adverse events, symptoms, extent, and treatment. 3. Presence or absence of measurement equipment failure. 4. Presence or absence of measurement cessation. 5.Recording of data monitoring: Inspired oxygen concentration, arterial blood gas analysis, blood pressure, heart rate, SpO2, ORI, SpHb of RootTM, perfusion index (PI), and pleth variability index (PVI)	—

Measure

Time frame

1. Basic information of patients: Gender, age, height, weight, date of surgery, diagnosis, operative procedure, sensor attachment site, and insertion site of the arterial pressure line. 2. Presence or absence of adverse events, symptoms, extent, and treatment. 3. Presence or absence of measurement equipment failure. 4. Presence or absence of measurement cessation. 5.Recording of data monitoring: Inspired oxygen concentration, arterial blood gas analysis, blood pressure, heart rate, SpO2, ORI, SpHb of RootTM, perfusion index (PI), and pleth variability index (PVI)

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Countries

Japan

Contacts

Public ContactTsuyoshi Isosu

Fukushima Medical University Department of Anesthesiology

masui@fmu.ac.jp024-547-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026