Clinical trial of ifenprodil for depression

Clinical trial of ifenprodil for depression - Ifenprodil for depression

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021111

Enrollment

Registered

2016-02-20

Start date

2014-05-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive episode

Interventions

Ifenprodil (10mg) 2 tabs po after each meal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who meet criteria for major depressive episode of DSM-IV-TR 2) Patients who responded poorly to the standard treatment with antidepressants or mood stabilizers.

Exclusion criteria

Exclusion criteria: 1) Post-intracranial bleeding and possibly still bleeding 2) Right after stroke 3) Hypotention 4) Tachycardia 5) On medication which causes bleeding tendency 6) pregnant or possibly pregnant 7) breastfeeding

Design outcomes

Primary

Measure	Time frame
Hamilton Depression Scale Before treatment, 1,2,4,6,8 weeks after starting treatment	—

Secondary

Measure	Time frame
Global Assessment of Functioning Before treatment, 1,2,4,6,8 weeks after starting treatment	—

Countries

Japan

Contacts

Public ContactAkihito Uezato

Tokyo Medical and Dental University Graduate School Department of Psychiatry and Behavioral Sciences

uezato-tmd@umin.ac.jp03-5803-5242

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026