The effect of hyaluronic acid injection in patient with wrist synovitis Uncontrolled exploratory clinical study

The effect of hyaluronic acid injection in patient with wrist synovitis Uncontrolled exploratory clinical study - The effect of hyaluronic acid injection in patient with wrist synovitis Uncontrolled exploratory clinical study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021082

Enrollment

Registered

2016-02-18

Start date

2016-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wrist synovitis

Interventions

ultrasound-guided intra-articular injection of hyaluronic acid in rheumatoid arthritis patients with wrist synovitis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)At least 20 years old when consent is given 2)The patients who have monoarthritis/ oligoarthritis with their wrist 3)The patient has been fully informed and has an adequate understanding about the study and has given voluntary written consent before participation

Exclusion criteria

Exclusion criteria: 1)No echo abnormal findings 2)The patients who want the other treatment such as biological therapy 3) Otherwise found ineligible as a subject by the researcher

Design outcomes

Primary

Measure	Time frame
Change of ultrasonography findings before and after injection of hyaluronic acid (once a week during the first five weeks, and after that, every 2 or more weeks depending on their symptoms )	—

Secondary

Measure	Time frame
Joint findings(swelling,pain)	—

Countries

Japan

Contacts

Public ContactHiroaki Hamada

University of Miyazaki Hospital Department of Orthopaedic Surgery

seikei@med.miyazaki-u.ac.jp0985850986

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026