Dehydrated
Conditions
Interventions
Group HS-12S
1st phase: Intake HS-12S - washed out, two days or more - 2nd phase: Intake mineral water
Group MW
1st phase: Intake mineral water - washed out, two days or more - 2nd phase: Intake HS-12S
Sponsors
Takeda Pharmaceutical Company Limited
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Healthy male who is able to provide written consent, aged 20 years or older then 2) Person weighing 50kg or over 3) Person between 18.5 and 24.9 of BMI 4) Person whose body fat percentage is 25% or less (measured by commercial scaler) 5) Person who has no abnormality to be enrolled
Exclusion criteria
Exclusion criteria: 1) Person with serious cardio-vascular, hepatic, renal, respiratory, endocrine or metabolic diseases, or who has a medical history of these disorders 2) Person who donated more than 200 mL of blood in the last one month, who donated more than 400 mL of blood in the last three months, and/or who donated blood components in the last two weeks 3) Person was included in other clinical studies in the last four months or who is now included in other clinical studies 4) Person considered not suitable for the study by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body weight after 1,2,3,4 hour(s) intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood tests; hematocrit, hemoglobin, Na, K, Cl, total protein, albumin, blood urea nitrogen, creatinine, glucose, serum osmolality Urine tests; urine volume, urine osmolality, Na, K, Cl, creatinine fractional excretion of sodium, water-electrolyte balance (Na, K, Cl) | — |
Countries
Japan
Contacts
Public ContactHiroshi Tsukikawa
Medical Co. LTA Sugioka Memorial Hospital Clinical Research Center Planning and Coordination Dept
Outcome results
None listed