Randomized controlled trial of efficacy of oligomeric formula (HINE E-GEL) vs polymeric formula (MEIN) after esophagectomy for esophageal cancer with gastric tube reconstruction

Randomized controlled trial of efficacy of oligomeric formula (HINE E-GEL) vs polymeric formula (MEIN) after esophagectomy for esophageal cancer with gastric tube reconstruction - Randomized controlled trial of efficacy of oligomeric formula (HINE E-GEL) vs polymeric formula (MEIN) after esophagectomy for esophageal cancer with gastric tube reconstruction

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021056

Enrollment

Registered

2016-02-16

Start date

2016-02-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Oligomeric formula Administration period: Until postoperative day 7 Dosage: Start at 10ml/h 10ml/h increase every day Polymeric formula Administration period: Un

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Esophageal cancer patients underwent esophagectomy and enterostomy Reconstruction methods: Gastric tube reconstruction Written informed consent.

Exclusion criteria

Exclusion criteria: Pt. without enterostomy Pt. without gastric tube reconstruction Pt. with a history of digestive surgery (except appendectomy) Pt. with colon or other digestive surgery simultaneously Pt. with an allergic of milk or soy or gelatin including nutrients Pt. with a tendency for loose stool (at 6 times or more of defecation per day) No informed consent is obtained

Design outcomes

Primary

Measure	Time frame
Frequency of diarrhea and fecal condition (Bristol stool form scale) Successful rate of administration of nutrients(7 postoperative days)	—

Secondary

Measure	Time frame
Postoperative complications, Nutrition status (Rapid turnover protein, weight change), Laboratory evidence, Length of stay in intensive care unit, Postoperative hospital stay, Tube obstruction	—

Countries

Japan

Contacts

Public ContactYu Ohkura

Toranomon hospital Department of Gastroenterological Surgery

yu.ohkura107@gmail.com03-3588-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026