Comparison of the analgesic effect for puncture between EMLA and Penless.

Comparison of the analgesic effect for puncture between EMLA and Penless. - The efficacy of EMLA and Penless.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020998

Enrollment

Registered

2016-02-12

Start date

2016-02-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The cases who receive general anesthesia or epidural anesthesia.

Interventions

EMLA was used for analgesia of puncture procedures , before 60 minutes of procedure. Penless was used for analgesia of puncture procedures , before 30 minutes of procedure.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients who receive general anesthesia. ASA-PS (American Society of Anesthesiologists - Physical Status) 1 or 2.

Exclusion criteria

Exclusion criteria: ?Past history of allergy for local anesthetics. ?Past history of contact dermatitis for ointment. ?Severe hepatic, renal or cardiovascular disease. ?Dermal abnormality on the puncture site. ?Methemogulobinemia ?Porphyria ?Sensory disturbance ?Pregnancy or lactation period ?Anesthesiologist determine that the patient is inappropriate for this study.

Design outcomes

Primary

Measure	Time frame
Visual Analog Scale (VAS) for the pain of puncture	—

Secondary

Measure	Time frame
Verbal Rating Scale (VRS), adverse event (cutaneous symptoms and local anesthetic toxicity)	—

Countries

Japan

Contacts

Public ContactNoyuki Hirata

Sapporo Medical University School of Medicine Anesthesiology

naohirata@mac.com011-611-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026