reflux esophagitis
Conditions
Interventions
Vonoprazan20mg-(washout period)-Lansoprazole30mg-(washout period)-Famotidine20mg
Lansoprazole30mg-(washout period)-Vonoprazan20mg-(washout period)-Famotidine20mg
Famotidine20mg-(washout period)-Lansop
Sponsors
Yokohama City University School of Medicine Department of Medical Education
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Patient who fills everything the following 1) Helicobacter pylori-negative male Patient 2) Patient of 20 years or more 3) Patient who gives written informed consent
Exclusion criteria
Exclusion criteria: The patient who collides with either the following assumes that it doesn't put it in to the examination 1) Drug allergy 2) Patient who took medicine that influences movement and function of digestive tract such as proton pump inhibitor, H2 blocker, and NSAIDs within 4 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intragastric pH by pH meter attached to the antimony pH electrode for 6 hour after administration | — |
Countries
Japan
Contacts
Public ContactHiroshi Iida
Yokohama City University School of Medicine Department of Medical Education
Outcome results
None listed