Cognitively normal older adults
Conditions
Interventions
All participants ware a diffuser necklace everyday for 8 weeks except while bathing and sleeping. They add 1-2 drops of 100% pure essential oil into the necklace everyday.
Sponsors
Keio University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age 65 to 89 years 2) Mini-Mental State Examination (MMSE) score of 24-30 3) Capacity to provide written informed consent
Exclusion criteria
Exclusion criteria: 1) Current or past history of alcohol abuse/dependence 2) Current of past history of epilepsy 3) Less than 7 years of formal education 4) Current use of antidepressant or antipsychotic medications and long term use of sedative hypnotics (including anti-anxiety) medications 5) History of psychiatric or neurological disorders that could affect cognitive functions 6) Current serious concomitant diseases (including hepatic, renal, or endocrinological illnesses) 7) Current diseases resulting in olfactory dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rey Auditory Verbal Learning Test (RAVLT) and Paced Auditory Serial Addition Test (PASAT) at baseline and 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Stait-Trait Anxiety Inventory (STAI) and Apathy Scale at baseline and 8 week | — |
Countries
Japan
Contacts
Public ContactTaisei Wake
Keio University School of Medicine Department of Neuropsychiatry
Outcome results
None listed