Analysis of the association between plasma xanthine oxidoreductase activity and atherosclerosis in the patients with metabolic diseases.

Analysis of the association between plasma xanthine oxidoreductase activity and atherosclerosis in the patients with metabolic diseases. - Analysis of the association between plasma xanthine oxidoreductase activity and atherosclerosis in the patients with metabolic diseases.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000020937

Enrollment

500

Registered

2016-02-08

Start date

2016-01-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Life-style related diseases.(Type 2 diabetes,dyslipidemia,hypertension,obesity)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.20 years and over 2.Patients without any hypouricemic agent and who have any of following life-style related diseases. (3-6) 3.Type 2 diabetes mellitus HbA1c6.5% and over(untreated) HbA1c4.8% and over(treated) 4.dyslipidemia 5.hypertension 6.obesity 7.Patients who themselves can voluntarily provide consent to participate in this study

Exclusion criteria

Exclusion criteria: 1.Ptients who are judged as inappropriate for inclusion by physicians. 2.Patients who can not be measured CAVI a.severe arteriosclerosis obliterans b.arterial fibrillation

Design outcomes

Primary

Measure	Time frame
Plasma xanthine oxidoreductase activity	—

Secondary

Measure	Time frame
1)body weight,blood pressure 2)uric acid,blood glucose,HbA1c,liver function,lipid parameter(TC,TG,HDL-C,LDL-C) 3)serum creatinine,urinary albumin 4)CAVI:Cardio-ankle vascular index	—

Countries

Japan

Contacts

Public ContactShou Tanaka

Toho University Sakura Medical Center Center of Diabetes,Endocrinology and Metabolism

shou.tanaka@med.toho-u.ac.jp043-462-8811

Outcome results