Study of the efficacy of the hyaluronic acid preparations (hyaluprotect) for the atrophic changes due to aging in the vagina and vulva.

Study of the efficacy of the hyaluronic acid preparations (hyaluprotect) for the atrophic changes due to aging in the vagina and vulva. - Study of the efficacy of the hyaluprotect for the atrophic vagina due to aging.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020909

Enrollment

Registered

2016-02-06

Start date

2016-02-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrophic changes due to aging of vagina and vulva.

Interventions

A hyaluronic acid preparation (hyaluprotect) 2-4 weeks estriol vaginal tablet 2-4 weeks moistjelly 2-4 weeks

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Menopausal for more than six months due to physiological or surgical reason. Complaint of dryness in the vagina. Atrophic findings in the vulva.

Exclusion criteria

Exclusion criteria: No contraindication of estriol. No bacterial infection. No use of other external medication for vagina within one week. No use of systemic estrogen within one month.

Design outcomes

Primary

Measure	Time frame
Sujjective symptoms and Vaginal Vestibule Maturation Value after 2,4 and 6 weeks.	—

Countries

Japan

Contacts

Public ContactMototsugu Fukaya

Tsurumai Kouen Clinic director

moto@earth.ocn.ne.jp052-164-0212

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026