The efficacy of ovarian preservation therapy in patients with systemic lupus erythematosus treated with cyclophosphamide pulse therapy - multi center observational study.

The efficacy of ovarian preservation therapy in patients with systemic lupus erythematosus treated with cyclophosphamide pulse therapy - multi center observational study. - The efficacy of ovarian preservation therapy in patients with systemic lupus erythematosus treated with cyclophosphamide pulse therapy

Status

Recruiting

Phases

Phase 3

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000020882

Enrollment

100

Registered

2016-02-07

Start date

2016-02-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

systemic lupus erythematosus

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients who had a diagnosis of SLE (fulfilled 4/11 American College of Rheumatology revised criteria) Patients who were eighteen years or older female. Patients who received more than 6 courses of IVCY Patients who provided a written informed concent.

Exclusion criteria

Exclusion criteria: Patients whom investigators judged inappropriate for this study.

Design outcomes

Primary

Measure	Time frame
The incidence of premenopausal ovarian insufficiency	—

Secondary

Measure	Time frame
parity pregnancy exacerbation of systemic lupus erythematosus	—

Countries

Japan

Contacts

Public ContactAtsushi Ihata

National Hospital Organization Yokohama Medical Center Department of Rheumatology

ihata-atsushi@yokohamamc.jp045-851-2621

Outcome results