Study on the arousal judgment of midazolam use intravenous sedation using the wearable eye movement apparatus TaikEye Lite -Part 2 Effects of flumazenil-

Study on the arousal judgment of midazolam use intravenous sedation using the wearable eye movement apparatus TaikEye Lite -Part 2 Effects of flumazenil- - Study on awakening judgment at the time of antagonist combination of intravenous sedation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020857

Enrollment

Registered

2016-02-05

Start date

2016-02-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Midazolam 0.05mg/kg was administered intravenously, and then 2mg administered flumazenil. Midazolam 0.05mg/kg was administered intravenously, and then administering a full saline.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The healty adult male and female volunteers participated this study.We obtained infprmed concent from all subjects.

Exclusion criteria

Exclusion criteria: Patient of two deggree or more of ASAclassification Age of under 20 Have a drug Allergy

Design outcomes

Primary

Measure	Time frame
1,Eye movement 2,Romberg's test 3,Electroencephalogram 4,Clinical findings 5,Sedation score 6,Vital signs	—

Countries

Japan

Contacts

Public ContactYosihide Saitou

The Nippon Dental University School of Life Dentistry at Niigata Department of Dental Anesthesiology

sai10yo@ngt.ndu.ac.jp0252671500

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026