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Role of cellular senescence in gastric carcinogenesis after eradication of Helicobacter pylori

Role of cellular senescence in gastric carcinogenesis after eradication of Helicobacter pylori - Cellulat senescence for post-eradication gastric carcinogenesis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000020849
Enrollment
60
Registered
2016-02-02
Start date
2014-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early gastric cancer

Interventions

Congo red chromoendoscopy

Sponsors

Tohoku university hospital, Division of Gastroenterology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patients who were taken examination for early gastric cancer at our department

Exclusion criteria

Exclusion criteria: 1) patients younger than 20 years old or older than 85 years old; 2) patients with history of chemotherapy, radiotherapy or upper abdominal surgery; 3) patients taking nonsteroidal anti-inflammatory drugs, antibiotics, or any anti-secretory drugs, such as proton pump inhibitors or H2 blockers; 4) patients with a serious general condition; 5) patients suffering from mental disorders; 6) patients who might be pregnancy; 7) patients with inappropriate biopsy specimens; and 8) patients who refused to participate in this study.

Design outcomes

Primary

MeasureTime frame
difference in the expression of senescence markers between the acid-secretion area and acid non-secretory area

Secondary

MeasureTime frame
difference in histological features between the acid secretion area and acid non-secretory area

Countries

Japan

Contacts

Public ContactKaname Uno

Tohoku University Gastroenterology

kaname-1@umin.ac.jp022-717-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026