Colonization of Lactobacillus rhamnosus L8020 in the oral cavity after intake of L8020-containing tablets

Colonization of Lactobacillus rhamnosus L8020 in the oral cavity after intake of L8020-containing tablets - Oral colonization of Lactobacillus rhamnosus L8020

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020795

Enrollment

Registered

2016-01-29

Start date

2016-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Volunteers ingest three L8020-containing tablets everyday after lunch for two weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy adult without dental caries, gingivitis and periodontal disease 2. Subject who will be able to prohibit foods with lactic acid bacteria, xylitol chewing gum and other tablets during experiment period 3. Subject who provide written informed consents

Exclusion criteria

Exclusion criteria: 1. Subject with allergy to dairy products 2. Subject with a history of antibiotic treatment within a month before experiment 3. Subject who may receive treatments of topical fluoride or povidone-iodine during experiment period

Design outcomes

Primary

Measure	Time frame
PCR detection for Lactobacillus in stimulated saliva 7 days before and 2, 7 and 14 days after intervention	—

Countries

Japan

Contacts

Public ContactTsuyoshi Taji

Integrated Health Sciences, Institute of Biomedical and Health Sciences, Hiroshima University Department of Oral Biology & Engineering

taji@hiroshima-u.ac.jp082-257-5797

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026