Comprehensive search of SNPs in patients with advanced renal cell carcinoma associated with efficacy and adverse events of molecular targeted therapies

Comprehensive search of SNPs in patients with advanced renal cell carcinoma associated with efficacy and adverse events of molecular targeted therapies - Search of SNPs associated with efficacy and adverse event of molecular targeted therapies for renal cell carcinoma

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020709

Enrollment

200

Registered

2016-01-25

Start date

2016-01-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal cell carcinoma

Interventions

blood sampling (5cc)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Renal cell carcinoma confirmed pathologically 2. Patients Treated or planed to be treated by molecular targeted therapy 3. Patients without severe complication in heart, lung, liver, kidney or other organ 4. Expected survival for 12 weeks or longer 5. Written informed consent

Exclusion criteria

Exclusion criteria: 1. HIV infection, or B/C active hepatitis 2. Active infection (grade 3 or more defined by CTCAE version 3) 3. Inadequate case in physicians opinion

Design outcomes

Primary

Measure	Time frame
Identify the SNPs in patients with advanced renal cell carcinoma associated with efficacy and adverse events of molecular targeted therapies	—

Secondary

Measure	Time frame
1. Identify the clinical factors in patients with advanced renal cell carcinoma associated with efficacy and adverse events of molecular targeted therapies 2. Identify the SNPs associated with oncogenesis of renal cell carcinoma	—

Countries

Japan

Contacts

Public ContactNoboru Nakaigawa

Yokohama City University Graduate School of Medicine Department of Urology

nakaigan@med.yokohama-cu.ac.jp045-787-2679

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026