The validation study for improvement of visual fatigue in healthy Japanese: a double-blind, randomized, placebo-controlled, and parallel trial

The validation study for improvement of visual fatigue in healthy Japanese: a double-blind, randomized, placebo-controlled, and parallel trial - The validation study for visual fatigue in healthy Japanese

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020684

Enrollment

Registered

2016-01-21

Start date

2016-01-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Period: 4 weeks Test food: Aronia tablet Dose: 5 tablets a day Usage: intake at optional timing Period: 4 weeks Test food: placebo tablet Dose: 5 tablets a day Usage: intake at optional timin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy Japanese men and women 2. Persons who are aware of visual fatigue 3. Persons who usually play TV games, use PC, or perform VDT for more than 4 hours a day. 4. Persons whose corrected visual acuity in both eyes is > 1.0, and who do not wear contact lenses.

Exclusion criteria

Exclusion criteria: 1. Persons who have previous medical history of malignant tumor, heart failure or myocardial infarction 2. Patients who are currently under the treatment for either atrial fibrillation, cardiac arrhythmia, hepatic disorder, renal disorder, cerebrovascular disorder, rheumatism, diabetes mellitus, dyslipidemia, hypertension or other chronic diseases 3. Patients who were diagnosed as presbyopia or are aware of presbyopia 4. Patients who have eye disease such as entropion or trichiasis 5. Patients who have uncorrected refractive errors 6. Patients who have astigmatism 7. Patients who have cause of visual fatigue except regulatory function such as nerve function, etc. 8. Persons who usually take pharmaceuticals (include herbal medicine), health-promoting diet and health food for the purpose of health maintenance 9. Persons who are allergic to medicines or foods related to the test food of this trial 10. Persons who have allergy to pollinosis 11. Persons who are pregnant, lactating, or planning to get pregnant during the trial period 12. Persons who were enrolled into other clinical trials within the last 3 months before agreeing to participate in this trial 13. Persons who are judged unsuitable for participating in this trial by physician

Design outcomes

Primary

Measure	Time frame
1. Miosis frequency (at 0 week and 4 weeks after) * Perform the test before and after VDT for 45 minutes	—

Secondary

Measure	Time frame
1. Flicker test (at 0 week and 4 weeks after) * Perform the test before and after VDT for 45 minutes 2. subjective symptoms (at 0 week and 4 weeks after)	—

Countries

Japan

Contacts

Public ContactNaoko SUZUKI

ORTHOMEDICO, Inc. R&D Department

nao@orthomedico.jp03-3818-0610

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026