Protective efficacy of ornithine for the pancreatic fistula after pancreatectomy

Protective efficacy of ornithine for the pancreatic fistula after pancreatectomy - Protective efficacy of ornithine for the pancreatic fistula after pancreatectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020602

Enrollment

280

Registered

2016-01-18

Start date

2016-01-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with pancreatectomy

Interventions

Single ingestion of ornithine 2.4g from 7days ago until 14days later of the surgery Control group: Patients without ingestion of ornithine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: [Ornithine intake group] 20years or older Patients who are possible to intake ornithine [Control group] Patients who were undergone pancreatectomy within 3years.

Exclusion criteria

Exclusion criteria: [Ornithine intake group] Less than 20 years old Patients who cannot understand study contents enough. Consent is not obtained from the patients. Patients who cannot take ornithine. Patients who were not undergone pancreatectomy for any reason. [Control group] Consent is not obtained from the patients.

Design outcomes

Primary

Measure	Time frame
Development and severity of pancreatic fistula (between 3 and 14 days after surgery)	—

Secondary

Measure	Time frame
Postoperative complications without pancreatic fistula and development of surgical site infection	—

Countries

Japan

Contacts

Public ContactYutaka Yutaka

Kyorin University, School of medicine Department of Surgery

ysuzuki@ks.kyorin-u.ac.jp+81-422-47-5511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026