Longitudinal Observational Cohort Study of Autosomal Dominant Alzheimer's Disease (ADAD) (DIAN-J)

Longitudinal Observational Cohort Study of Autosomal Dominant Alzheimer's Disease (ADAD) (DIAN-J) - Longitudinal Observational Cohort Study of Autosomal Dominant Alzheimer's Disease (ADAD) (DIAN-J)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000020576

Enrollment

Registered

2016-01-15

Start date

2016-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autosomal Dominant Alzheimer disease (ADAD)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ;Written informed consent obtained from the participant and collateral source prior to any study-related rocedures. ;child of an affected individual(clinically or by testing) in a pedigree with a known mutation for ADAD. ;Participant is cognitively normal. ;Participant is a native speaker of Japanese and is fluent in Japanese communication.

Exclusion criteria

Exclusion criteria: ;Participant has a medical or psychiatric illness that would interfere in completing initial and follow-up assessments. ;Participant has advanced cognitive impairment requiring nursing home-level care.

Design outcomes

Primary

Measure	Time frame
clinical, cognitive, genetic, imaging, and biomarker	—

Countries

Japan

Contacts

Public ContactHiroyuki Shimada

Osaka City University Graduate School of Medicine Department of Diagnostic and Interventional Radiology

h.shimada@med.osaka-cu.ac.jp06-6646-6185

Outcome results