health male adults
Conditions
Interventions
1) After tDCS active stimulation (2mA, 15min), we investigate each examination below
(a) brain MRI (b) [11C] raclopride PET scan (6mCi, single injection) (c) cognitive function test 2) After tDCS sham stimulation (2mA, 15min), we investigate each examination below
(a) brain MRI (b) [11C] raclopride PET scan (6mCi, single injection) (c) cognitive function test
Sponsors
National Institute of Radiological Sciences
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Subjects who are healthy and don't have medical history of psychiatry, neurological and other severe physical diseases 2) Subjects who have the ability to provide informed consent 3) Subjects who are between 20 and 40 years old, right-handed and non-smoker
Exclusion criteria
Exclusion criteria: 1) Subjects with a pacemaker or other metallic medical device in the body (brain clip, bolts, etc.) 2) Subjects with claustrophobia 3) From the standpoint of radiation exposure from a nuclear medicine scan, subjects who have participated in other nuclear medicine scans as healthy volunteers in the 6 months prior to the start of this study 4) Subjects who take antihistamine drugs within one week of the study 5) Subjects who are considered to be inappropriate for participation by doctors with responsibilities in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of binding potential of D2 receptor, functional connectivity and cognitive function after tDCS | — |
Countries
Japan
Contacts
Public ContactKazuko Suzuki
National Institute of Radiological Sciences Molecular Imaging Center
Outcome results
None listed