Healthy volunteer
Conditions
Interventions
Ingestion of supplement containing N-acetyl glucosamine, proteoglycan complex and lutein for 12 weeks
Ingestion of placebo without N-acetyl glucosamine, proteoglycan complex and lutein for 12 weeks
Sponsors
Soiken Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subject, aged from 30 to 65 years Males and females with uncomfortable feeling of knee 2) Subject, be diagnosed KLgrade 0 or 1 3) Subject, upon briefing of the content of the present study, fully understanding and agreeing to its objective; and being able to personally sign a written informed consent
Exclusion criteria
Exclusion criteria: 1)Subjects having a medical history of rheumatism 2)Subjects who have leg pain or numbness 3)Subjects who have injury of semi-lunar disc or the other knee joint disease 4)Subjects receiving treatment for osteoarthritis 5)Subject receiving treatment for serious liver, renal, cardio-vascular, respiratory, endocrine, or metabolic disorders 6)Subject presenting known allergy or history of hypersensitivity to gelatin, crab and salmon 7)For female subject: pregnancy or breast feeding, or possibility of pregnancy, or intention to be pregnant during the study 8)Subject having blood sample of 200 ml or more taken (e.g., donated blood) within 1 month, or 400 ml or more within 3 months prior to the start of the present study 9)Subject who took part in another clinical trial within 3 months prior to the start of the present study or who is currently taking part in another clinical trial 10)Subject deemed unsuitable by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| JKOM and Knee Society Score(ver 2011) | — |
Secondary
| Measure | Time frame |
|---|---|
| knee joint subjective symptoms(VAS) | — |
Countries
Japan
Contacts
Public ContactTomohiro Sugino
Soiken Inc. President & CEO
Outcome results
None listed