Clinical trial on the usefulness and the safety of imidazole antifungal topical agent; ketoconazole cream for acne vulgaris

Clinical trial on the usefulness and the safety of imidazole antifungal topical agent; ketoconazole cream for acne vulgaris - Clinical trial on the usefulness and the safety of imidazole antifungal topical agent; ketoconazole cream for acne vulgaris

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020494

Enrollment

Registered

2016-03-01

Start date

2016-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acne vulgaris

Interventions

apply to half side of the face -A group R

ketoconazole cream, L

nadifloxacin cream 0.5g twice a day, topical, administration period: 12weeks apply to half side of the face -B group L

ketoconazole cream, R

nadifloxacin cream 0.5g twice a day, topical, administration period: 12weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: bisymmetrically acne vulgaris on face

Exclusion criteria

Exclusion criteria: -Patient who takes steroid or antifungus. -Patient who has history of contact dermatitis due to external medicine which contains antifungus or antibiotic. -If the attending physician has determined ineligible as a subject of this study.

Design outcomes

Primary

Measure	Time frame
inflammatory acne and comedo)by ketoconazole cream and nadifloxacin cream	—

Secondary

Measure	Time frame
Change of visual analogue scale score by the subjects three months after the start of this study	—

Countries

Japan

Contacts

Public ContactAkiko Yagami

Fujita Health University Department of dermatology

ayagami@fujita-hu.ac.jp0562-93-9256

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026