Healthy adults
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy females aged from 35 to 45 years old. 2. Person whose skin with chapping or person with dry skin. 3. Person with wrinkle problem 4. Person with dullness skin. 5. Person whom skin state changes with body condition change (example: Stress, fatigue and lack of sleep) easily. 6. People who can agree to participate in a test spontaneously in document. 7. Person who can agree with blood pressure taking by fingers. 8. Person who can stop use of the essence during a test period
Exclusion criteria
Exclusion criteria: 1. Person who have abnormalities in the skin of a measured region 2. Person who are out patients. 3. Person with the anamnesis of an alcohol or drug dependence. 4. Person who have possibilities for emerging allergy to cosmetics and foods. 5. Persons who are pregnant or lactating, or planned to become pregnant during a test period. 6. Person who participate in the other clinical studies within 4 weeks in the past, or person who have a schedule which participates in other clinical studies during a test period. 7. Person who are judges as unsuitable for the study by the investigator for other reason. 8. Those to whom the person himself/herself and a family are working for the cosmetics company, the food company, an advertising agency, investigation and consultant business, and a mass media-related company. 9. Patients with vascular function disorder, or person who have severe poor circulation. 10. Person who was abnormal by blood pressure or electrocardiogram inspection. 11. Current smoker.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the stratum corneum water content, the transepidermal water loss, the skin color, the skin viscoelasticity, the stratum corneum cell size, blood flow measurement, and the dermatological assessment after the repeated treatment for 2, 4 and 8 weeks with the carbonate cosmetics | — |
Countries
Japan
Contacts
Kao Corporation R&D Health Beauty Products Research