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Treatment of neonatal hemochromatosis with high-dose intravenous immunoglobulin during pregnancy

Treatment of neonatal hemochromatosis with high-dose intravenous immunoglobulin during pregnancy - Treatment of neonatal hemochromatosis with high-dose intravenous immunoglobulin during pregnancy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000020469
Enrollment
2
Registered
2016-01-13
Start date
2010-09-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal haemochromatosis

Interventions

The treatment consisted of intravenous immunoglobulin administered weekly at a dose of 1 g per kg bodyweight from the 18th week until the end of gestation.

Sponsors

Department of Pediatrics, School of Medicine, Institute of Medical Pharmaceutical and Health Sciences, Kanazawa University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women who were pregnant were identified as candidates for treatment if they had a previous infant or fetus affected with neonatal hemochromatosis and, therefore, were considered to be at high risk to have another.

Exclusion criteria

Exclusion criteria: Women who had allergy for immunoglobulin.

Design outcomes

Primary

MeasureTime frame
Assessment of the effectiveness in preventing the severity of recurrent neonatal haemochromatosis: monitoring of the mother's health and the progress of pregnanacy monitering of the infant's health, liver function and development

Countries

Japan

Contacts

Public ContactYusuke Mitani

School of Medicine, Institute of Medical Pharmaceutical and Health Sciences, Kanazawa University Department of Pediatrics

ped.yusuke@gmail.com076-265-2313

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026