Intranasal Premedication with Dexmedetomidine and midazolam in ophthalmic surgery for pediatrics, are they really equally effective?

Intranasal Premedication with Dexmedetomidine and midazolam in ophthalmic surgery for pediatrics, are they really equally effective? - Intranasal Premedication with Dexmedetomidine and midazolam in ophthalmic surgery for pediatrics, are they really equally effective?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020446

Enrollment

Registered

2016-02-01

Start date

2015-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

now we are writing the discussion and conclusion of the study

Interventions

patient received 0.5 mg/kg midazolam intranasally half hour before anesthesia starting and asses the degree of sedation and separation from parents patient received intranasal dexmedetomidine 1 micro

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who were submitted for elective ophthalmic surgery. 2. ASA 1,2 3. Age: 2-6 years

Exclusion criteria

Exclusion criteria: 1. Parent refusal. 2. Patients suffering from congenital cardiac disease. 3. History of allergy to any of the studied drugs. 4. Any nasal disorders that may hinder nasal administration of the drugs as repeated nasal bleeding or nasal tumors.

Design outcomes

Primary

Measure	Time frame
prove that intranasal dexmedetomedine is superior to midazolam as sedative preanesthetic drug in pediatric surgery	—

Countries

Africa

Contacts

Public ContactGhada Fouad Mohamed

Mansoura university ophthalmology center, mansoura faculty of medicine, mansoura university anethesia and intensive care department

ghadafouad2013@hotmail.com+81-1008081333

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026