Biomarkers predictive for clinical efficacy of bronchial thermoplasty in patients with asthma

Biomarkers predictive for clinical efficacy of bronchial thermoplasty in patients with asthma - Biomarkers for bronchial thermoplasty

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000020443

Enrollment

Registered

2016-01-06

Start date

2016-01-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial asthma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Unstable asthma requiring regular maintenance medication that includes high dose inhaled corticosteroid and long acting beta2 agonist -Willingness and ability to give written Informed Consent -Willingness and ability to comply with the study protocol, including requirements for taking and abstaining from medications

Exclusion criteria

Exclusion criteria: -Use of an internal or external pacemaker or internal cardiac defibrillator -Known sensitivity to medications required to perform bronchoscopy, including lidocaine, atropine and benzodiazepines -lower respiratory tract infection -Unstable asthma with an increased does of systemic corticosteroid within 2 weeks -Bleeding diathesis, platelet dysfunction, thrombocytopenia with platelet count less than 125,000/mm2 or known coagulopathy (INR > 1.5) -Any active disease left untreated

Design outcomes

Primary

Measure	Time frame
Biomarker discovery for clinical efficacy of bronchial thermoplasty	—

Countries

Japan

Contacts

Public ContactNorihiro Harada

Juntendo University school of medicine Department of respiratory medicine

nor@juntendo.ac.jp03-5802-1063

Outcome results