Multicenter retrospective observational study of carbon-ion radiation therapy for hepatocellular carcinoma (J-CROS 1504)

Multicenter retrospective observational study of carbon-ion radiation therapy for hepatocellular carcinoma (J-CROS 1504) - Multicenter retrospective observational study of carbon-ion radiation therapy for hepatocellular carcinoma (J-CROS 1504)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000020441

Enrollment

250

Registered

2016-01-05

Start date

2015-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Pathollogically or clinically diagnosed hepatocellular carcinoma. 2) All lesions were included in the single radiation field. 3) Treated by hypofractionated treatment course.(Patients treated by more than 4 fractions are analysed separately) 4) Tumor size is Measurable. 5) cN0M0 (accrdiong to UICC(International Union Against Cancer) TMN classification of Malignant tumours 7th edition) 6) Patients without any other active malignancies. 7) Absence of uncontrolled ascites 8) Child-Pugh score of the patient is from 5 points to 9 points. 9) Perfomance status of the patient is from 0 to 2. 10) Written informed concent is obtained.

Exclusion criteria

Exclusion criteria: 1) History of radiation therapy to the lesion of interest. 2) Presence of major portal or hepatic vein invasion. 3) History of hepatocellular carcinoma in except for the lesion of interest. 4) Patient with severe comorbidity.

Design outcomes

Primary

Measure	Time frame
Overall survival	—

Secondary

Measure	Time frame
Local control rate, Acute and rate toxicity (within 3 months and 3 months or later)	—

Countries

Japan

Contacts

Public ContactTatsuya Ohno

Gunma University Heavy Ion Medical Center

tohno@gunma-u.ac.jp027-220-8378

Outcome results