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Anatomical vs. Non-Anatomical resection of colorectal liver metastases: a randomized controlled trial

Anatomical vs. Non-Anatomical resection of colorectal liver metastases: a randomized controlled trial - ANA-RCT

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000020410
Enrollment
400
Registered
2015-12-31
Start date
2013-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal liver metastases

Interventions

The patients who has colorectal liver metasis less than 4 Couinaud segment were randomized equally to limited resection. The patients who has colorectal liver metasis less than 4 Couinaud segment were

Sponsors

Department of Digestive Surgery, Nihon University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1 Typical colorectal liver metastasis in enhanced CT and were resectable for surgical treatment less than 4 Couinaud segments. 2 No evidence of massive vessel invasion 3 Good liver functional reserve Child-Pugh score less than 7point. 4 Judged as "Resectable tumor status" in our surgical review board. 5 Good general condition ECOG performance status: 0-2. 6 Optimal other organ status.

Exclusion criteria

Exclusion criteria: 1 Have active other cancer (within 5year) Except for carcinoma in situ. 2 OMI or unstable angina within 6 month before operation. 3 Bad prumonary status Idiopathic pulmonary fibrosis, severe emphysema. 4 iodine hypersensitivity Bad renal function: serum creatinin >1.5 mg/dL. 5 unstable mental disease. 6 possivility of pregnant

Design outcomes

Primary

MeasureTime frame
3-year recurrence-free survival

Secondary

MeasureTime frame
Overall survival Intraoperative blood loss Distance of surgical maergin postoperative complication

Countries

Japan

Contacts

Public ContactShintaro Yamazaki

Nihon University School of Medicine Department of Digestive Surgery

yamazaki-nmed@umin.ac.jp03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026