The short-term and long-term effect on meibomian gland dysfunction with dry eye by Diquafosol Sodium eye drop

The short-term and long-term effect on meibomian gland dysfunction with dry eye by Diquafosol Sodium eye drop - The effect on MGD with dry eye by Diquafosol Sodium eye drop

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020408

Enrollment

Registered

2016-01-01

Start date

2016-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal eyes

Interventions

Diquafosol eyedrop 6 times a day for 4 weeks Artificial tear eyedrop 6 times a day for 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Normal eyes without dry eye symptoms

Exclusion criteria

Exclusion criteria: Normal subjects with any other ocular disease (except cataract, refractive error) . The history of contact lens wear. Subjects without written informed consent.

Design outcomes

Primary

Measure	Time frame
Lipid layer thickness	—

Secondary

Measure	Time frame
Symtoms, tear-film break up time (TBUT), tear meniscus, meibography, Schirmer tess	—

Countries

Japan

Contacts

Public ContactArita Reiko

Itoh Clinic Department of Ophthalmology

arita.reiko@gmail.com048-686-5588

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026