Comparison of continuous and intermittent administration of patient controlled epidural analgesia after major joint replacement surgery

Comparison of continuous and intermittent administration of patient controlled epidural analgesia after major joint replacement surgery - Epidural PIB study of TKA and THA

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020401

Enrollment

Registered

2016-01-01

Start date

2014-10-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total hip arthroplasty and Total knee althroplasty

Interventions

A prospective, randomized, double-blinded, controlled trial Comparing two protocols: A)Continuous administration: 0.2%Ropivacaine 4ml/hr. B)Intermittent administration: 0.2%Ropivacaine 6ml ever

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: elective unilateral TKA or THA epidural and general anesthesia age 20 to 90 year ability to follow study protocol ASA-PS 1 to 2.

Exclusion criteria

Exclusion criteria: contradiction for epidural anesthesia chronic (>3 months) opioid use allergies to local anesthetics preexisting neuropathy on the limb decline to participate

Design outcomes

Primary

Measure	Time frame
Pain score (VAS 0-100) of 0 to 3 POD Pain interception level	—

Secondary

Measure	Time frame
the use of regional analgesics, the use of another analgesic methods, Patient satisfaction, Patient mobility and side effects.	—

Countries

Japan

Contacts

Public ContactAyanoo Oiwa

Toho University School of Medicine Anesthesiology

ayano.nakao@med.toho-u.ac.jp03-3762-4151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026