Prospective study of efficacy of Negative-pressure wound therapy (NPWT) for dirty abdominal wound after lower gastrointestinal perforation.

Prospective study of efficacy of Negative-pressure wound therapy (NPWT) for dirty abdominal wound after lower gastrointestinal perforation. - Prospective study of efficacy of Negative-pressure wound therapy (NPWT) for dirty abdominal wound after lower gastrointestinal perforation.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000020391

Enrollment

Registered

2015-12-30

Start date

2015-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower gastrointestinal perforation

Interventions

For the patients with dirty abdominal wound after lower gastrointestinal perforation, primary skin closure is not perfomed. Therefore, negative pressure wound therapy is started within 3 days and cont

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1, The patients with dirty abdominal wound after lower gastrointestinal perforation 2, Older than 20 years old 3, Estimated survival is over 6 months 4, Documented informed consent

Exclusion criteria

Exclusion criteria: 1, Naked blood vessel suspected of bleeding or surgical site infection to directly contact to other organs or the presence of fistula to abdominal cavity. 2, The presence of organ/space surgical site infection 3, The patient corresponding to the VAC treatment system Contraindications. 4, As determined by the principal investigator or the sub-investigator the subject is not adequate to participate in the study.

Design outcomes

Primary

Measure	Time frame
The rate of surgical site infection within 30days from wound suturing.	—

Secondary

Measure	Time frame
The postoperative hospital stay, the presence of reopened wound, the presence and degree of adverse events, The duration of wound healing	—

Countries

Japan

Contacts

Public ContactMamoru Uemura

Osaka University Graduate School of Medicine Department of Gastroenterological Surgery

muemura@gesurg.med.osaka-u.ac.jp81-6-6879-3251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026