Patients who had one or more of cardiovascular risks
Conditions
Interventions
None listed
Sponsors
Jichi Medical University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with one more than risk factors as follows: 1) diabetes or glucose tolerance disorder (under the treatment with fasting blood-sugar level 110 mg/dl or above, 75gOGTT (in 2 hours level 140mg/dl or above) 2) dyslipidemia (under the treatment or total cholesterol level above 240mg/dl) 3) Hypertension a. under treatment b. clinic blood pressure 140/90 mmHg or above c. home blood pressure 130/80 mmHg or above 4) Current smoking 5) Renal disease (positive proteinuria or serum creatinine level 1.1mg/dl or above) 6) Atrial fibrillation 7) metabolic syndrome 8) chronic obstructive pulmonary disease 9) sleep apnea syndrome
Exclusion criteria
Exclusion criteria: 1) ischemic heart disease, cerebrovascular disease (except for asymptomatic or transient ischemic attack), aortic dissection, chronic arterial obstruction or history of heart failure requiring hospitalization within 6 months. 2) hemodialysis patients 3) Having other severe diseases (cancer, connective tissue disease) 4) Unable to obtain an informed consent due to underage (less than 20 years old), cognitive dysfunction and so forth. 5) Unable to walk unaided (cane walking is considered 'able to walk without aided')
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All cause death, cardiovascular death, sudden death, ischemic heart disease (acute myocardial infarction, angina pectoris), cerebrovascular disease (cerebral infarction, cerebral embolism, intracerebral bleeding, subarachnoid hemorrhage). (Unknown cerebrovascular disease, silent cerebral infarction or transient ischemic attack are excluded). | — |
Secondary
| Measure | Time frame |
|---|---|
| Newly developed symptomatic arteriosclerosis obliterans, aortic dissection, heart failure requiring hospitalization, de novo diabetes; chronic hemodialysis, atrial fibrillation, newly developed hypertension. | — |
Countries
Japan
Contacts
Public ContactSatoshi Hoshide
Jichi Medical University School of Medicine Division of Cardiovascular Medicine, Department of Medicine
Outcome results
None listed